Human p23 (PTGES3) activation kit by CRISPRa

CAT#: GA107350

PTGES3 CRISPRa kit - CRISPR gene activation of human prostaglandin E synthase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTGES3
• Locus ID: 10728
• Kit Components:

  GA107350G1, PTGES3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107350G2, PTGES3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107350G3, PTGES3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282601, NM_001282602, NM_001282603, NM_001282604, NM_001282605, NM_006601, NR_104219
• Synonyms: cPGES; P23; TEBP
• Summary: This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]