Human ALDH1L1 activation kit by CRISPRa
CAT#: GA107422
ALDH1L1 CRISPRa kit - CRISPR gene activation of human aldehyde dehydrogenase 1 family member L1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | ALDH1L1 |
Locus ID | 10840 |
Kit Components | GA107422G1, ALDH1L1 gRNA vector 1 in pCas-Guide-CRISPRa GA107422G2, ALDH1L1 gRNA vector 2 in pCas-Guide-CRISPRa GA107422G3, ALDH1L1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001270364, NM_001270365, NM_012190, NM_144776, NR_072979 |
Synonyms | 10-fTHF; 10-FTHFDH; FDH; FTHFD |
Summary | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN413720 | ALDH1L1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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