Human USP19 activation kit by CRISPRa

CAT#: GA107443

USP19 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP19
• Locus ID: 10869
• Kit Components:

  GA107443G1, USP19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107443G2, USP19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107443G3, USP19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199160, NM_001199161, NM_001199162, NM_006677, NM_001351098, NM_001351099, NM_001351100, NM_001351101, NM_001351102, NM_001351103, NM_001351104, NM_001351105, NM_001351106, NM_001351107, NM_001351108
• Synonyms: ZMYND9
• Summary: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]