Human GLIPR1 activation kit by CRISPRa

CAT#: GA107560

GLIPR1 CRISPRa kit - CRISPR gene activation of human GLI pathogenesis related 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLIPR1
• Locus ID: 11010
• Kit Components:

  GA107560G1, GLIPR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107560G2, GLIPR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107560G3, GLIPR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006851
• Synonyms: CRISP7; GLIPR; RTVP1
• Summary: This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]