Human EMILIN1 activation kit by CRISPRa

CAT#: GA107644

EMILIN1 CRISPRa kit - CRISPR gene activation of human elastin microfibril interfacer 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EMILIN1
• Locus ID: 11117
• Kit Components:

  GA107644G1, EMILIN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107644G2, EMILIN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107644G3, EMILIN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007046
• Synonyms: EMI; EMILIN; gp115
• Summary: This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009]