Human BTN2A1 activation kit by CRISPRa

CAT#: GA107647

BTN2A1 CRISPRa kit - CRISPR gene activation of human butyrophilin subfamily 2 member A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BTN2A1
• Locus ID: 11120
• Kit Components:

  GA107647G1, BTN2A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107647G2, BTN2A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107647G3, BTN2A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001197233, NM_001197234, NM_007049, NM_078476
• Synonyms: BK14H9.1; BT2.1; BTF1; BTN2.1; DJ3E1.1
• Summary: This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]