Human NUDT3 activation kit by CRISPRa

CAT#: GA107687

NUDT3 CRISPRa kit - CRISPR gene activation of human nudix hydrolase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUDT3
• Locus ID: 11165
• Kit Components:

  GA107687G1, NUDT3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107687G2, NUDT3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107687G3, NUDT3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006703
• Synonyms: DIPP; DIPP-1; DIPP1
• Summary: NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]). [supplied by OMIM, Feb 2011]