Human CYPIVF8 (CYP4F8) activation kit by CRISPRa

CAT#: GA107778

CYP4F8 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 4 subfamily F member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP4F8
• Locus ID: 11283
• Kit Components:

  GA107778G1, CYP4F8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107778G2, CYP4F8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107778G3, CYP4F8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007253
• Synonyms: CPF8; CYPIVF8
• Summary: This gene, CYP4F8, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and functions as a 19-hydroxylase of prostaglandins in seminal vesicles. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F3, is approximately 18 kb away. [provided by RefSeq, Jul 2008]