Human PNK (PNKP) activation kit by CRISPRa

CAT#: GA107779

PNKP CRISPRa kit - CRISPR gene activation of human polynucleotide kinase 3'-phosphatase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PNKP
• Locus ID: 11284
• Kit Components:

  GA107779G1, PNKP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107779G2, PNKP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107779G3, PNKP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007254
• Synonyms: AOA4; EIEE10; MCSZ; PNK
• Summary: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay. [provided by RefSeq, Sep 2010]