Human MRAS activation kit by CRISPRa

CAT#: GA107825

MRAS CRISPRa kit - CRISPR gene activation of human muscle RAS oncogene homolog

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MRAS
• Locus ID: 22808
• Kit Components:

  GA107825G1, MRAS gRNA vector 1 in pCas-Guide-CRISPRa

  GA107825G2, MRAS gRNA vector 2 in pCas-Guide-CRISPRa

  GA107825G3, MRAS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001085049, NM_001252090, NM_001252091, NM_001252092, NM_001252093, NM_012219
• Synonyms: M-RAs; R-RAS3; RRAS3
• Summary: This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]