Human SAPS1 (PPP6R1) activation kit by CRISPRa

CAT#: GA107868

PPP6R1 CRISPRa kit - CRISPR gene activation of human protein phosphatase 6 regulatory subunit 1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol PPP6R1
Locus ID 22870
Kit Components

GA107868G1, PPP6R1 gRNA vector 1 in pCas-Guide-CRISPRa

GA107868G2, PPP6R1 gRNA vector 2 in pCas-Guide-CRISPRa

GA107868G3, PPP6R1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_014931
Synonyms KIAA1115; PP6R1; SAP190; SAPS1
Summary Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]). [supplied by OMIM, Nov 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.