Human Rho guanine exchange factor 15 (ARHGEF15) activation kit by CRISPRa

CAT#: GA107894

ARHGEF15 CRISPRa kit - CRISPR gene activation of human Rho guanine nucleotide exchange factor 15

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARHGEF15
• Locus ID: 22899
• Kit Components:

  GA107894G1, ARHGEF15 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107894G2, ARHGEF15 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107894G3, ARHGEF15 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014958, NM_025014, NM_173728
• Synonyms: ARGEF15; E5; Ephexin5; Vsm-RhoGEF
• Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene. [provided by RefSeq, Aug 2010]