Human TNIK activation kit by CRISPRa

CAT#: GA107995

TNIK CRISPRa kit - CRISPR gene activation of human TRAF2 and NCK interacting kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TNIK
• Locus ID: 23043
• Kit Components:

  GA107995G1, TNIK gRNA vector 1 in pCas-Guide-CRISPRa

  GA107995G2, TNIK gRNA vector 2 in pCas-Guide-CRISPRa

  GA107995G3, TNIK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001161560, NM_001161561, NM_001161562, NM_001161563, NM_001161564, NM_001161565, NM_001161566, NM_015028, NR_027767
• Synonyms: TRAF2 and NCK interacting kinase
• Summary: Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]