Human EXPH5 activation kit by CRISPRa

CAT#: GA108026

EXPH5 CRISPRa kit - CRISPR gene activation of human exophilin 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXPH5
• Locus ID: 23086
• Kit Components:

  GA108026G1, EXPH5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108026G2, EXPH5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108026G3, EXPH5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144763, NM_001144764, NM_001144765, NM_001308019, NM_015065
• Synonyms: SLAC2-B; SLAC2B
• Summary: The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein is thought to be involved in exosome secretion and intracellular vesicle trafficking. Reduced expression of this gene results in keratin filament defects. Mutations in this gene have been associated with some cases of epidermolysis bullosa, an inherited skin fragility disorder. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]