Human ATP11B activation kit by CRISPRa

CAT#: GA108119

ATP11B CRISPRa kit - CRISPR gene activation of human ATPase phospholipid transporting 11B (putative)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATP11B
• Locus ID: 23200
• Kit Components:

  GA108119G1, ATP11B gRNA vector 1 in pCas-Guide-CRISPRa

  GA108119G2, ATP11B gRNA vector 2 in pCas-Guide-CRISPRa

  GA108119G3, ATP11B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014616
• Synonyms: ATPIF; ATPIR
• Summary: P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine. [supplied by OMIM, Feb 2005]