Human DNMBP activation kit by CRISPRa

CAT#: GA108177

DNMBP CRISPRa kit - CRISPR gene activation of human dynamin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNMBP
• Locus ID: 23268
• Kit Components:

  GA108177G1, DNMBP gRNA vector 1 in pCas-Guide-CRISPRa

  GA108177G2, DNMBP gRNA vector 2 in pCas-Guide-CRISPRa

  GA108177G3, DNMBP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318326, NM_001318327, NM_015221
• Synonyms: ARHGEF36; TUBA
• Summary: This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]