Human DMXL2 activation kit by CRISPRa

CAT#: GA108210

DMXL2 CRISPRa kit - CRISPR gene activation of human Dmx like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DMXL2
• Locus ID: 23312
• Kit Components:

  GA108210G1, DMXL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108210G2, DMXL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108210G3, DMXL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001174116, NM_001174117, NM_015263
• Synonyms: PEPNS; RC3
• Summary: This gene encodes a protein with 12 WD domains. Proteins with WD domains are involved in many functions including participation in signal transduction pathways. Participation of the encoded protein in regulation of the Notch signaling pathway has been demonstrated in vitro using several human cell lines (PMID:20810660). A gene encoding a similar protein is located on chromosome 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]