Human KCNH3 activation kit by CRISPRa

CAT#: GA108294

KCNH3 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily H member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNH3
• Locus ID: 23416
• Kit Components:

  GA108294G1, KCNH3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108294G2, KCNH3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108294G3, KCNH3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001314030, NM_012284
• Synonyms: BEC1; ELK2; Kv12.2
• Summary: The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]