Human NPTXR activation kit by CRISPRa

CAT#: GA108326

NPTXR CRISPRa kit - CRISPR gene activation of human neuronal pentraxin receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPTXR
• Locus ID: 23467
• Kit Components:

  GA108326G1, NPTXR gRNA vector 1 in pCas-Guide-CRISPRa

  GA108326G2, NPTXR gRNA vector 2 in pCas-Guide-CRISPRa

  GA108326G3, NPTXR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014293, NM_058178
• Synonyms: NPR
• Summary: This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]