Human MACF1 activation kit by CRISPRa

CAT#: GA108345

MACF1 CRISPRa kit - CRISPR gene activation of human microtubule actin crosslinking factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MACF1
• Locus ID: 23499
• Kit Components:

  GA108345G1, MACF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108345G2, MACF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108345G3, MACF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012090, NM_033024, NM_033044
• Synonyms: ABP620; ACF7; MACF; OFC4
• Summary: This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]