Human Cbl c (CBLC) activation kit by CRISPRa

CAT#: GA108442

CBLC CRISPRa kit - CRISPR gene activation of human Cbl proto-oncogene C


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CBLC
Locus ID 23624
Kit Components

GA108442G1, CBLC gRNA vector 1 in pCas-Guide-CRISPRa

GA108442G2, CBLC gRNA vector 2 in pCas-Guide-CRISPRa

GA108442G3, CBLC gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001130852, NM_012116
Synonyms CBL-3; CBL-SL; RNF57
Summary This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.