Human FUS2 (NAT6) activation kit by CRISPRa

CAT#: GA108511

NAA80 CRISPRa kit - CRISPR gene activation of human N(alpha)-acetyltransferase 80, NatH catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAT6
• Locus ID: 24142
• Kit Components:

  GA108511G1, NAT6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108511G2, NAT6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108511G3, NAT6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001200016, NM_001200018, NM_012191
• Synonyms: FUS-2; FUS2
• Summary: This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]