Human RAD54B activation kit by CRISPRa

CAT#: GA108534

RAD54B CRISPRa kit - CRISPR gene activation of human RAD54 homolog B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAD54B
• Locus ID: 25788
• Kit Components:

  GA108534G1, RAD54B gRNA vector 1 in pCas-Guide-CRISPRa

  GA108534G2, RAD54B gRNA vector 2 in pCas-Guide-CRISPRa

  GA108534G3, RAD54B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001205262, NM_001205263, NM_012415, NM_134434
• Synonyms: RDH54
• Summary: The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]