Human AUTS2 activation kit by CRISPRa

CAT#: GA108725

AUTS2 CRISPRa kit - CRISPR gene activation of human activator of transcription and developmental regulator AUTS2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AUTS2
• Locus ID: 26053
• Kit Components:

  GA108725G1, AUTS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108725G2, AUTS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108725G3, AUTS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127231, NM_001127232, NM_015570
• Synonyms: FBRSL2; MRD26
• Summary: This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2014]