Human PTPN20B (PTPN20) activation kit by CRISPRa

CAT#: GA108749

PTPN20 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase non-receptor type 20

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTPN20
• Locus ID: 26095
• Kit Components:

  GA108749G1, PTPN20 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108749G2, PTPN20 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108749G3, PTPN20 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042357, NM_001042358, NM_001042359, NM_001042360, NM_001042361, NM_001042362, NM_001042363, NM_001042364, NM_001042365, NM_001320681, NM_001320682, NM_001320683, NM_001320684, NM_001320685, NM_001320686, NM_001320688, NM_001320689, NM_001320690, NM_001320691, NM_015605, NM_001352521, NM_001352522, NM_001352523, NM_001352524, NM_001352525, NM_001352526, NM_001352527, NM_001352528, NM_001352529, NM_001352530, NM_001352531, NM_001352532, NM_001352533, NM_001352534, NM_001352535, NM_001352536, NM_001352537, NM_001352538, NM_001352539, NM_001352540, NM_001352541, NM_001352542, NM_001352543, NM_001352544, NM_001352545, NM_001352546, NM_001352547, NM_001352548, NM_001352549, NM_001352550, NM_001352551, NM_001352552, NM_001352553, NM_001352554, NM_001352555, NR_148022, NR_148023, NR_148024
• Synonyms: bA42B19.1; bA142I17.1; CT126; PTPN20A; PTPN20B
• Summary: The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]