Human SEZ6L2 activation kit by CRISPRa

CAT#: GA108865

SEZ6L2 CRISPRa kit - CRISPR gene activation of human seizure related 6 homolog like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEZ6L2
• Locus ID: 26470
• Kit Components:

  GA108865G1, SEZ6L2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108865G2, SEZ6L2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108865G3, SEZ6L2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114099, NM_001114100, NM_001243332, NM_001243333, NM_012410, NM_201575
• Synonyms: PSK-1
• Summary: This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]