Human HTF9C (TRMT2A) activation kit by CRISPRa

CAT#: GA108979

TRMT2A CRISPRa kit - CRISPR gene activation of human tRNA methyltransferase 2 homolog A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRMT2A
• Locus ID: 27037
• Kit Components:

  GA108979G1, TRMT2A gRNA vector 1 in pCas-Guide-CRISPRa

  GA108979G2, TRMT2A gRNA vector 2 in pCas-Guide-CRISPRa

  GA108979G3, TRMT2A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001257994, NM_001331039, NM_022727, NM_182984
• Synonyms: HTF9C
• Summary: The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]