Human DKK4 activation kit by CRISPRa

CAT#: GA109018

DKK4 CRISPRa kit - CRISPR gene activation of human dickkopf WNT signaling pathway inhibitor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DKK4
• Locus ID: 27121
• Kit Components:

  GA109018G1, DKK4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109018G2, DKK4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109018G3, DKK4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014420
• Synonyms: DKK-4
• Summary: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2. [provided by RefSeq, Jul 2008]