Human GLS2 activation kit by CRISPRa

CAT#: GA109048

GLS2 CRISPRa kit - CRISPR gene activation of human glutaminase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLS2
• Locus ID: 27165
• Kit Components:

  GA109048G1, GLS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109048G2, GLS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109048G3, GLS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001280796, NM_001280797, NM_001280798, NM_013267, NM_138566
• Synonyms: GA; GLS; hLGA; LGA
• Summary: The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]