Human GMPPB activation kit by CRISPRa

CAT#: GA109315

GMPPB CRISPRa kit - CRISPR gene activation of human GDP-mannose pyrophosphorylase B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GMPPB
• Locus ID: 29925
• Kit Components:

  GA109315G1, GMPPB gRNA vector 1 in pCas-Guide-CRISPRa

  GA109315G2, GMPPB gRNA vector 2 in pCas-Guide-CRISPRa

  GA109315G3, GMPPB gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013334, NM_021971
• Synonyms: MDDGA14; MDDGB14; MDDGC14
• Summary: This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]