Human G2A (GPR132) activation kit by CRISPRa

CAT#: GA109321

GPR132 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 132

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPR132
• Locus ID: 29933
• Kit Components:

  GA109321G1, GPR132 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109321G2, GPR132 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109321G3, GPR132 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278694, NM_001278695, NM_001278696, NM_013345
• Synonyms: G2A
• Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]