Human POMT2 activation kit by CRISPRa

CAT#: GA109339

POMT2 CRISPRa kit - CRISPR gene activation of human protein O-mannosyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POMT2
• Locus ID: 29954
• Kit Components:

  GA109339G1, POMT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109339G2, POMT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109339G3, POMT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013382
• Synonyms: LGMD2N; MDDGA2; MDDGB2; MDDGC2
• Summary: The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS). [provided by RefSeq, Oct 2008]