Human RDH8 activation kit by CRISPRa

CAT#: GA109444

RDH8 CRISPRa kit - CRISPR gene activation of human retinol dehydrogenase 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RDH8
• Locus ID: 50700
• Kit Components:

  GA109444G1, RDH8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109444G2, RDH8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109444G3, RDH8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015725
• Synonyms: PRRDH; SDR28C2
• Summary: This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014]