Human ASAP1 activation kit by CRISPRa

CAT#: GA109450

ASAP1 CRISPRa kit - CRISPR gene activation of human ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASAP1
• Locus ID: 50807
• Kit Components:

  GA109450G1, ASAP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109450G2, ASAP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109450G3, ASAP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001247996, NM_018482, NM_001362924, NM_001362925, NM_001362926
• Synonyms: AMAP1; CENTB4; DDEF1; PAG2; PAP; ZG14P
• Summary: This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]