Human GRIM19 (NDUFA13) activation kit by CRISPRa

CAT#: GA109545

NDUFA13 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit A13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFA13
• Locus ID: 51079
• Kit Components:

  GA109545G1, NDUFA13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109545G2, NDUFA13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109545G3, NDUFA13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015965
• Synonyms: B16.6; CDA016; CGI-39; GRIM-19; GRIM19
• Summary: This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. [provided by RefSeq, Oct 2009]