Human SEPSECS activation kit by CRISPRa

CAT#: GA109555

SEPSECS CRISPRa kit - CRISPR gene activation of human Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEPSECS
• Locus ID: 51091
• Kit Components:

  GA109555G1, SEPSECS gRNA vector 1 in pCas-Guide-CRISPRa

  GA109555G2, SEPSECS gRNA vector 2 in pCas-Guide-CRISPRa

  GA109555G3, SEPSECS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001159728, NM_016955, NM_153825
• Synonyms: LP; MGC161491; Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; SLA; SLA/LP; soluble liver antigen/liver pancreas antigen
• Summary: The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec). [provided by RefSeq, Mar 2011]