Human NDUFAF1 activation kit by CRISPRa

CAT#: GA109567

NDUFAF1 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase complex assembly factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFAF1
• Locus ID: 51103
• Kit Components:

  GA109567G1, NDUFAF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109567G2, NDUFAF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109567G3, NDUFAF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016013, NR_045620
• Synonyms: CGI-65; CGI65; CIA30
• Summary: This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]