Human COQ4 activation kit by CRISPRa

CAT#: GA109580

COQ4 CRISPRa kit - CRISPR gene activation of human coenzyme Q4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COQ4
• Locus ID: 51117
• Kit Components:

  GA109580G1, COQ4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109580G2, COQ4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109580G3, COQ4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001305942, NM_016035
• Synonyms: CGI-92; COQ10D7
• Summary: This gene encodes a component of the coenzyme Q biosynthesis pathway. Coenzyme Q, an essential component of the electron transport chain, shuttles electrons between complexes I or II to complex III of the mitochondrial transport chain. This protein appears to play a structural role in stabilizing a complex that contains most of the coenzyme Q biosynthesis enzymes. Mutations in this gene are associated with mitochondrial disorders linked to coenzyme Q deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]