Human ASB3 activation kit by CRISPRa

CAT#: GA109592

ASB3 CRISPRa kit - CRISPR gene activation of human ankyrin repeat and SOCS box containing 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASB3
• Locus ID: 51130
• Kit Components:

  GA109592G1, ASB3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109592G2, ASB3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109592G3, ASB3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001201965, NM_016115, NM_145863
• Synonyms: ASB-3
• Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2011]