Human CRBN activation kit by CRISPRa

CAT#: GA109633

CRBN CRISPRa kit - CRISPR gene activation of human cereblon

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRBN
• Locus ID: 51185
• Kit Components:

  GA109633G1, CRBN gRNA vector 1 in pCas-Guide-CRISPRa

  GA109633G2, CRBN gRNA vector 2 in pCas-Guide-CRISPRa

  GA109633G3, CRBN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173482, NM_016302
• Synonyms: MRT2; MRT2A
• Summary: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]