Human EPLIN (LIMA1) activation kit by CRISPRa

CAT#: GA109824

LIMA1 CRISPRa kit - CRISPR gene activation of human LIM domain and actin binding 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LIMA1
• Locus ID: 51474
• Kit Components:

  GA109824G1, LIMA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109824G2, LIMA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109824G3, LIMA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113546, NM_001113547, NM_001243775, NM_016357
• Synonyms: EPLIN; SREBP3
• Summary: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]