Human ISYNA1 activation kit by CRISPRa

CAT#: GA109826

ISYNA1 CRISPRa kit - CRISPR gene activation of human inositol-3-phosphate synthase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ISYNA1
• Locus ID: 51477
• Kit Components:

  GA109826G1, ISYNA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109826G2, ISYNA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109826G3, ISYNA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001170938, NM_001170939, NM_001253389, NM_016368, NR_045573, NR_045574
• Synonyms: INO1; INOS; IPS; IPS-1; IPS 1
• Summary: This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]