Human TH1L (NELFCD) activation kit by CRISPRa

CAT#: GA109836

NELFCD CRISPRa kit - CRISPR gene activation of human negative elongation factor complex member C/D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NELFCD
• Locus ID: 51497
• Kit Components:

  GA109836G1, NELFCD gRNA vector 1 in pCas-Guide-CRISPRa

  GA109836G2, NELFCD gRNA vector 2 in pCas-Guide-CRISPRa

  GA109836G3, NELFCD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016397, NM_198976
• Synonyms: HSPC130; negative elongation factor proteins C and D; NELF-C; NELF-D; OTTHUMP00000031415; TH1; TH1 drosophila homolog; TH1, NELF-C, NELF-D, HSPC130; TH1-like (Drosophila); TH1-like protein
• Summary: The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini. [provided by RefSeq, Jul 2008]