Human PIGT activation kit by CRISPRa

CAT#: GA109897

PIGT CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class T

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGT
• Locus ID: 51604
• Kit Components:

  GA109897G1, PIGT gRNA vector 1 in pCas-Guide-CRISPRa

  GA109897G2, PIGT gRNA vector 2 in pCas-Guide-CRISPRa

  GA109897G3, PIGT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001184728, NM_001184729, NM_001184730, NM_015937, NR_047691, NR_047692, NR_047693, NR_047694, NR_047695
• Synonyms: CGI-06; MCAHS3; NDAP; PNH2
• Summary: This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]