Human GPRC5B activation kit by CRISPRa

CAT#: GA109952

GPRC5B CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor class C group 5 member B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPRC5B
• Locus ID: 51704
• Kit Components:

  GA109952G1, GPRC5B gRNA vector 1 in pCas-Guide-CRISPRa

  GA109952G2, GPRC5B gRNA vector 2 in pCas-Guide-CRISPRa

  GA109952G3, GPRC5B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304771, NM_016235
• Synonyms: RAIG-2; RAIG2
• Summary: This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]