Human RAP80 (UIMC1) activation kit by CRISPRa

CAT#: GA109959

UIMC1 CRISPRa kit - CRISPR gene activation of human ubiquitin interaction motif containing 1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol UIMC1
Locus ID 51720
Kit Components

GA109959G1, UIMC1 gRNA vector 1 in pCas-Guide-CRISPRa

GA109959G2, UIMC1 gRNA vector 2 in pCas-Guide-CRISPRa

GA109959G3, UIMC1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001199297, NM_001199298, NM_001317961, NM_016290, NR_146149, NR_146150
Synonyms RAP80; X2HRIP110
Summary This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.