Human CROP (LUC7L3) activation kit by CRISPRa

CAT#: GA109972

LUC7L3 CRISPRa kit - CRISPR gene activation of human LUC7 like 3 pre-mRNA splicing factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LUC7L3
• Locus ID: 51747
• Kit Components:

  GA109972G1, LUC7L3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109972G2, LUC7L3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109972G3, LUC7L3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330330, NM_006107, NM_016424
• Synonyms: CRA; CREAP-1; CROP; hLuc7A; LUC7A; OA48-18
• Summary: This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009]