Human Myozenin 2 (MYOZ2) activation kit by CRISPRa

CAT#: GA109988

MYOZ2 CRISPRa kit - CRISPR gene activation of human myozenin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYOZ2
• Locus ID: 51778
• Kit Components:

  GA109988G1, MYOZ2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109988G2, MYOZ2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109988G3, MYOZ2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016599
• Synonyms: C4orf5; CMH16; CS-1
• Summary: The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]