Human ADA2 activation kit by CRISPRa

CAT#: GA109997

ADA2 CRISPRa kit - CRISPR gene activation of human adenosine deaminase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADA2
• Locus ID: 51816
• Kit Components:

  GA109997G1, ADA2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109997G2, ADA2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109997G3, ADA2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282225, NM_001282226, NM_001282227, NM_001282228, NM_001282229, NM_017424, NM_177405
• Synonyms: ADA2; ADGF; IDGFL; PAN; SNEDS
• Summary: This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]