Human IL20 Receptor alpha (IL20RA) activation kit by CRISPRa

CAT#: GA110029

IL20RA CRISPRa kit - CRISPR gene activation of human interleukin 20 receptor subunit alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL20RA
• Locus ID: 53832
• Kit Components:

  GA110029G1, IL20RA gRNA vector 1 in pCas-Guide-CRISPRa

  GA110029G2, IL20RA gRNA vector 2 in pCas-Guide-CRISPRa

  GA110029G3, IL20RA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278722, NM_001278723, NM_001278724, NM_014432
• Synonyms: CRF2-8; IL-20R-alpha; IL-20R1; IL-20RA
• Summary: This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]